[Generated for Academic Purposes] Journal: Journal of Neural Engineering and Regenerative Medicine Volume: 12, Issue: 4, Date: December 2016
The peripheral nerve is a biological cable of remarkable complexity. Following traumatic transection, surgical reanastomosis often yields poor functional recovery due to axonal misdirection and denervation atrophy. For decades, functional electrical stimulation (FES) has been the standard for restoring movement, but it suffers from a lack of fiber-type selectivity (activating sensory and motor fibers simultaneously) and rapid onset of fatigue (Prochazka, 2015). nerve -2016-
In 2016, a team led by Dr. K. L. Montgomery at Stanford University introduced a transformative solution: optogenetic nerve stimulation. By rendering specific motor axons light-sensitive, they bypassed the injury site entirely, offering a new paradigm for nerve repair. [Generated for Academic Purposes] Journal: Journal of Neural